Basic Information
VIS ID
TVIS44016063
Fusion event
HTLV-1-LOC105374294 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
194704645/194983916 (Hg38)
End
194704645/194983916 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374294
Nearest miRNA
hsa-let-7g/Upstream/5153907; hsa-mir-3137/Downstream/150590;
Nearest TSS
ENST00000440867/Upstream/156026; ENST00000458531/Downstream/103456;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/295600, chr3-CpG: 29/Downstream/81332
Nearby gene
XXYLT1(No orient, 84363)
Upstream sequence
TCACACCATTGTCTGAGCTTACAGACCCATGGCTCTCCAGTAGCATAGGCCACGCTGCCAGAAGCCCCTCCAAACACTCACCCAGACTTGAGTGTGGTCC
Downstream sequence
CCAGATACACCCAACATACTCTCTGGGCACCATCAGAGAAAACTCAGACCCAGTACCTGCCATGAAAGAACTTGAGATGGAAGAGGGAGAAAAACTTATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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