Basic Information
VIS ID
TVIS44016081
Fusion event
HTLV-1-ULK4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
42003528/41962036 (Hg38)
End
42003528/41962036 (Hg38)
Orient
+
Location type
UTR5
Target gene
ULK4
Nearest miRNA
hsa-mir-12127/Upstream/2823770; hsa-let-7g/Downstream/2152176;
Nearest TSS
ENST00000440867/Upstream/42; ENST00000418790/Downstream/19;
Nearest CpG islands
chr3-CpG: 72/Target, None/Upstream, None/Downstream
Upstream sequence
GGCCTGCGCGCTCTTCCGCGACCGCTTAGGCAGACACGAACTCAGACTCGTAGCTACTAAAACCGCCACTGCCACGCACCTGGTAGCTAAGTCAAGAAAA
Downstream sequence
GAGTCCAGTCCACTTGGCTGCTCCCGCGGTTGCGCGCATCTCGGCCTCTGCCTCAGGACAGGTCCACAGGCCCAAGAATGGGGGAGAAAGCAGTGAAGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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