VISDB Viral Integration Site DataBase

VIS ID

TVIS44016088

Fusion event

HTLV-1-MAP4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

p21.31

Reference genome

Start

End

47898303/47856813 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-551b-3p ; hsa-mir-484 ; hsa-mir-339-5p ; hsa-mir-331-3p ; hsa-mir-328-3p ; hsa-mir-23b-3p ; hsa-mir-196a-5p ; hsa-mir-100-5p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-1207-5p ; hsa-mir-1827 ; hsa-mir-1913 ; hsa-mir-2682-5p ; hsa-mir-3151-5p ; hsa-mir-324-3p ; hsa-mir-34b-5p ; hsa-mir-34c-5p ; hsa-mir-4421 ; hsa-mir-4446-3p ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-449c-5p ; hsa-mir-4720-3p ; hsa-mir-4763-3p ; hsa-mir-486-3p ; hsa-mir-491-5p ; hsa-mir-5587-3p ; hsa-mir-5693 ; hsa-mir-5699-3p ; hsa-mir-6132 ; hsa-mir-6721-5p ; hsa-mir-6742-5p ; hsa-mir-6748-3p ; hsa-mir-6762-3p ; hsa-mir-6773-3p ; hsa-mir-6796-3p ; hsa-mir-6796-5p ; hsa-mir-6829-5p ; hsa-mir-6836-5p ; hsa-mir-6860 ; hsa-mir-6879-3p ; hsa-mir-6882-3p ; hsa-mir-99a-3p ; hsa-mir-99b-3p

Nearest miRNA

hsa-mir-12127/Upstream/7184; hsa-let-7g/Downstream/339751;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/6759, chr3-CpG: 98/Downstream/231622

Upstream sequence

accgcgcccgcccTGAGGGAAGAGAGTTTTGCCTTCACCTTATCTGGCCTGTGGTGGCTAGCCTTCTGGGATACCAGGTCTGCCAGCCAGTGTGCCTGCT

Downstream sequence

GCTACAGCAGTCCTACTCACAAATCTGCTGTAGACCCAGGAACTAGGACACGAGGCTGCTAGGGGACTACCCAAGGCAAGAGCCCAGCCTCCGCACAGCG