Basic Information
VIS ID
TVIS44016093
Fusion event
HTLV-1-LOC105376934 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p26.1
Reference genome
GRCh37/hg19
Start
5062486/5020801 (Hg38)
End
5062486/5020801 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105376934
Nearest miRNA
hsa-let-7g/Downstream/229376;
Nearest TSS
ENST00000440867/Upstream/40569; ENST00000444332/Downstream/101419;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/33583, chr3-CpG: 35/Downstream/5550
Nearby gene
BHLHE40(+35621) ;
Upstream sequence
AGGAAAACTTCACGCAGAGACTGATGGGTACAGAGGCATGAATTGGAGTGGGAGGAATCCCAAGTACCTTGGTTTCCCCCTTCCCAGTGAGCTAGAACAT
Downstream sequence
GATCTTGGTCAAGCCGGAGTGCTGATGTAGGGGCCATGGCCGGGGGTTCCTCTAGGGGTGGCAGTCATGCTTATGAGGGTGAGTGCTTTAAAAATGACTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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