Basic Information
VIS ID
TVIS44016160
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
GRCh37/hg19
Start
116276166/115355010 (Hg38)
End
116276166/115355010 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/698156; hsa-mir-1305/Downstream/10152249;
Nearest TSS
ENST00000502981/Upstream/241134; ENST00000604093/Downstream/943866;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/755234, chr4-CpG: 21/Downstream/1244265
Nearby gene
NDST4(-241134) ;
Nearest cancer related gene
NDST4(TSG, -241134) ;
Upstream sequence
tacgtctgtggaacttgtattgggccctgaattgattctctggctccctgatgtttgaagtccactgtgctggggagccgaggaatggcagctgcattcg
Downstream sequence
agtgttagtgaatgaagaggtgcctgcttccctgtggtgttctgcacagtggcagatacaaggcagctgggagtggggagtgggtgcccctgctagagac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate