Basic Information
VIS ID
TVIS44016179
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.3
Reference genome
GRCh37/hg19
Start
134481134/133559979 (Hg38)
End
134481134/133559979 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/8052672; hsa-mir-1305/Downstream/9783481;
Nearest TSS
ENST00000502981/Upstream/405086; ENST00000503009/Downstream/450711;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/407506, chr4-CpG: 21/Downstream/1384246
Nearby gene
PCDH10(+365369) ;
Nearest cancer related gene
PCDH10(TSG, +365369) ;
Upstream sequence
CAAATTAGGGCACGCCCCAAATCAAGTGCACTCAATGCAGTGGCTTGTCACACTAAAAAAAATGTAACATAGGAAAGTTAGTGGAATAAATATCACCCAC
Downstream sequence
ACCCTGCAGCTAGTCCTGAGACCCTAACTAATGGTTTTACAACCTCCTCTATGAATACTGTCACTGGATCCTTGGGATGttgctcgacctttgcctgctg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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