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TVIS44016191
Basic Information
VIS ID
TVIS44016191
Fusion event
HTLV-1-SMARCA5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
144456199/143535046 (Hg38)
End
144456199/143535046 (Hg38)
Orient
+
Location type
Intronic
Target gene
SMARCA5
miRNAs that regulate target gene
hsa-mir-877-3p
;
hsa-mir-424-5p
;
hsa-mir-99a-5p
;
hsa-mir-100-5p
;
hsa-let-7a-2-3p
;
hsa-mir-101-3p
;
hsa-let-7g-3p
;
hsa-mir-99b-5p
;
hsa-mir-3667-5p
;
hsa-mir-606
;
hsa-mir-3133
;
hsa-mir-4511
;
hsa-mir-25-3p
;
hsa-mir-32-5p
;
hsa-mir-92a-3p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-92b-3p
;
hsa-mir-186-5p
;
hsa-mir-8070
;
hsa-mir-6736-5p
;
hsa-mir-4701-3p
;
hsa-mir-1262
;
hsa-mir-7703
;
hsa-mir-500a-3p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-542-3p
;
hsa-mir-661
;
hsa-mir-767-5p
;
hsa-mir-4487
;
hsa-mir-558
;
hsa-mir-3160-3p
;
hsa-mir-4679
;
hsa-mir-6776-5p
;
hsa-mir-4793-3p
;
hsa-mir-766-3p
;
hsa-mir-6742-3p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-508-5p
;
hsa-mir-107
;
hsa-mir-103a-3p
;
hsa-let-7c-3p
;
hsa-mir-493-5p
;
hsa-mir-144-3p
;
hsa-mir-151a-5p
Nearest miRNA
hsa-mir-12113/Upstream/191511; hsa-mir-1305/Downstream/2873537;
Nearest TSS
ENST00000502981/Upstream/20411;
ENST00000515531/Downstream/8587;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/20856
,
chr4-CpG: 47/Downstream/24342
Upstream sequence
CAAAATGCAAAGGGAATGGTATGTATTCTCAGATGTACTTGATAGCACTATTGATTCTTCCCTAAATTTCATGTGTATTTTGTTTTCCTAATTTGTGTCT
Downstream sequence
TCATGGAATTCCAATTTGCTGGATTGAACTCAACCTGAAAAGAGTTTTCTTGTCACGTAGTATAGGACTTGCTCATTAAGTTCGTTATAGAAAGTTTTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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