Basic Information
VIS ID
TVIS44016229
Fusion event
HTLV-1-LOC105377564 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
180896452/179975299 (Hg38)
End
180896452/179975299 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377564
Nearest miRNA
hsa-mir-12113/Upstream/5551435; hsa-mir-1305/Downstream/2193994;
Nearest TSS
ENST00000502981/Upstream/509994; ENST00000512480/Downstream/783739;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2532745, chr4-CpG: 160/Downstream/82586
Nearby gene
LINC00290(-1088791) ;
Upstream sequence
ATCTAACTATCCATGCTTAAATCACAGCTTTGGTTCTGAGAGAAAACAGGAGAGAGTGAGTGAGAGTTTAAGTGATTTTTGAGGTGATGAGATATGGTAC
Downstream sequence
CTTAAGCAAAGGTATTAGCATTCTTCAATTCTTAATATTAGACACTACTAGGGATGATATCTTTAGAGTAATTTGGCAGCATAGTTAATCCTCTGATCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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