Basic Information
VIS ID
TVIS44016246
Fusion event
HTLV-1-LOC105374528 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
23738636/23737013 (Hg38)
End
23738636/23737013 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
LOC105374528
Nearest miRNA
hsa-mir-12113/Upstream/1221628; hsa-mir-1243/Downstream/783179;
Nearest TSS
ENST00000502981/Upstream/3434; ENST00000499715/Downstream/25914;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1220588, chr4-CpG: 266/Downstream/733064
Nearby gene
PPARGC1A(-55008) ;
Upstream sequence
TAAGTAATGGTACTTACAATGTTCTACTGATCATTCTACTGAGTTAAAGGACTATAAGTATTAAATATATGACTGcctataatagtaatcattatactct
Downstream sequence
ctacatacttgtttatgtttctgtctccctaaaaaccaggagcatcttgaagtcagagattatgtcttcttttaaatgttttattctccctcattaagca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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