VISDB Viral Integration Site DataBase

VIS ID

TVIS44016249

Fusion event

HTLV-1-TBC1D19 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p15.2

Reference genome

Start

End

26686188/26684566 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4279 ; hsa-mir-4744 ; hsa-mir-5009-3p ; hsa-mir-4662b ; hsa-mir-4426 ; hsa-mir-4647 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-6765-5p ; hsa-mir-3672 ; hsa-mir-6864-3p ; hsa-mir-6745 ; hsa-mir-3165 ; hsa-mir-363-5p ; hsa-mir-3656 ; hsa-mir-6087 ; hsa-mir-3197 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-631 ; hsa-mir-3661 ; hsa-mir-4649-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-151a-3p ; hsa-mir-198 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-548q ; hsa-mir-4257 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-665 ; hsa-mir-1273e ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-5002-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-34b-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6134 ; hsa-mir-6840-3p

Nearest miRNA

hsa-mir-12113/Upstream/2164276; hsa-mir-1243/Downstream/2135016;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/100389, chr4-CpG: 58/Downstream/172684

Upstream sequence

aggttccacctgtggttgcgtgcttggttcatctggccatgctcaggttacgtgaccttcaacctggaggtccatggcaactgaaaaacagctcataact

Downstream sequence

gtgttacatagaagttgaaccagattggtctggtgtagctaacacTTTATGTGTAATATAGGATATGAATAATTCTGAATTAATATTAGGCAGTTTAAAA