Basic Information
VIS ID
TVIS44016258
Fusion event
HTLV-1-LINC02505 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
36532070/36530448 (Hg38)
End
36532070/36530448 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02505
Nearest miRNA
hsa-mir-12113/Upstream/104020; hsa-mir-1243/Downstream/711462;
Nearest TSS
ENST00000502981/Upstream/138038; ENST00000501725/Downstream/52282;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/285681, chr4-CpG: 173/Downstream/713180
Nearby gene
MIR1255B1(-104020) ;
Upstream sequence
TTTGTTTATATATTATATAAAGCTGCTTTTCAAAAAGCTAATGTGGTAGTAGATACTAATAGAAGCCTCAGTGCTGAAGGATAAAATACATACCTCCCAC
Downstream sequence
AGAGTTGTCAGACATATATTTCTTCATAGTCCTATAATAATTTATCTGGTACTGTTTTGCTTTTGCTCTATCCAAAATAAGATATTACTAAAATAATATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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