Basic Information
VIS ID
TVIS44016267
Fusion event
HTLV-1-KCTD8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p13
Reference genome
GRCh37/hg19
Start
44318793/44316776 (Hg38)
End
44318793/44316776 (Hg38)
Orient
-
Location type
Intronic
Target gene
KCTD8
Nearest miRNA
hsa-mir-12113/Upstream/3814657; hsa-mir-1243/Downstream/3335893;
Nearest TSS
ENST00000502981/Upstream/299714; ENST00000513775/Downstream/130837;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1659243, chr4-CpG: 174/Downstream/130593
Upstream sequence
gtggtggctcatgcctgtaatcccagcactttgggaggccgaggcgggccaatcacaaggtcaggagatcgagaccatcctggctaacacagtgaaaccc
Downstream sequence
catctctactaaaaatacgaaaaaaaaaaaaaaaaaaaaaaaaaaaagaagataagccgagcttggtggccggcgcctgtagtcccagatacttgggagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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