VISDB Viral Integration Site DataBase

VIS ID

TVIS44016282

Fusion event

HTLV-1-OCIAD1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p11

Reference genome

Start

End

48837314/48835297 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-513b-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-6886-3p ; hsa-mir-938 ; hsa-mir-6841-3p ; hsa-mir-4719 ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-548g-3p ; hsa-mir-5089-5p ; hsa-mir-4665-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-1273g-3p ; hsa-mir-6890-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-4438 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-2681-3p

Nearest miRNA

hsa-mir-12113/Upstream/1182554; hsa-mir-1243/Downstream/3877385;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/3745, chr4-CpG: 53/Downstream/70978

Upstream sequence

tgctgggattacaggtgtgagccactgcgcctggccCTGAAGTAGTTTTATATGTGGTGAGACAAAGCTAATACATGAAACACTTAGAGATTAAGTGTGT

Downstream sequence

AACTGCAGAAGACTTTTTAAAGAGATAAATTAATTAGAATTGACTTACTGAAATTGAAAAATTTGAATAACTTTTGAGATTTTAAAACTCAAAATTTTCT