Basic Information
VIS ID
TVIS44016287
Fusion event
HTLV-1-SCFD2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
53860237/52994070 (Hg38)
End
53860237/52994070 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4B
Target gene
SCFD2
Nearest miRNA
hsa-mir-12113/Upstream/281323; hsa-mir-1243/Downstream/7928549;
Nearest TSS
ENST00000502981/Upstream/48381; ENST00000510668/Downstream/371871;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/131237, chr4-CpG: 43/Downstream/371471
Upstream sequence
CTTGGGCCCCAGCCCTCCTCCCAGCCCTGAGGCTGGTCCCGCTCTAGACAGCTGGGTTTGGAGCTGCTCCTGTTCAGGGGTAACTCCCCACAGGCCAGGA
Downstream sequence
GTGGGGCTGTTCCTGGGGCATCCTCAGGCCAGCAGTTCCTCTGAATGGTTGGGGGAGAAATGAAAAGACACCTGGAGGGCTGTGGATCACAGCCAGGTGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate