VISDB Viral Integration Site DataBase

VIS ID

TVIS44016310

Fusion event

HTLV-1-UGT2B4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

q13.3

Reference genome

Start

End

70367494/69501776 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-574-5p ; hsa-mir-433-3p ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-4693-5p ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-511-3p ; hsa-mir-513b-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-3941 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-4643 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-8066 ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-193b-5p ; hsa-mir-6890-5p ; hsa-mir-2392 ; hsa-mir-541-5p ; hsa-mir-4455 ; hsa-mir-3149 ; hsa-mir-568 ; hsa-mir-4789-5p ; hsa-mir-8068 ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-4704-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-297 ; hsa-mir-1229-3p ; hsa-mir-2117 ; hsa-mir-567 ; hsa-mir-1304-3p ; hsa-mir-656-3p ; hsa-mir-510-5p ; hsa-mir-512-5p

Nearest miRNA

hsa-mir-12113/Upstream/3224848; hsa-mir-1243/Downstream/7071792;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/1151573, chr4-CpG: 55/Downstream/1186361

Upstream sequence

gttttcaggtatagggttagtatagagcttctggggaaggggcaggctgtcatctttgctgtttgggcaacctaaccaatcctgcctttgaggtttggag

Downstream sequence

gttccaaggtgaccaggggctgatatgtacccccagcacagcacagctgctctatgaaaatgtggtcagctgctctacttagactccacgtagctctgtg