VISDB Viral Integration Site DataBase

VIS ID

TVIS44016319

Fusion event

HTLV-1-SORCS2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p16.1

Reference genome

Start

End

7567418/7565691 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1274b ; hsa-mir-23b-3p ; hsa-mir-6818-5p ; hsa-mir-1273e ; hsa-mir-636 ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-766-5p ; hsa-mir-873-5p ; hsa-mir-205-3p ; hsa-mir-141-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-7111-5p ; hsa-mir-548l ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6752-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-3692-3p ; hsa-mir-29b-2-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-642b-5p ; hsa-mir-6070 ; hsa-mir-671-3p ; hsa-mir-5088-3p ; hsa-mir-4453 ; hsa-mir-4538 ; hsa-mir-3157-5p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-4691-3p ; hsa-mir-1306-5p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-520f-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6800-3p ; hsa-mir-6853-3p ; hsa-mir-1206 ; hsa-mir-567

Nearest miRNA

hsa-mir-378d-1/Upstream/105573; hsa-mir-12113/Downstream/439610;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/54990, chr4-CpG: 19/Downstream/25951

Upstream sequence

ggtgatggtaatgatgatgatataatgatgataatgatggtgatgatggtgatttttatggtgatgatgtgatgatgctgatgatgtgatgatggtgatg

Downstream sequence

tttatgatgatgacggtggtgatggtgctgtgatggtgatgatgatgatgatgtgaaagtgatggtgatggtgtcggtggtgatgatgtgatgatggata