Basic Information
VIS ID
TVIS44016331
Fusion event
HTLV-1-ARHGAP24 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.23
Reference genome
GRCh37/hg19
Start
86448326/85527173 (Hg38)
End
86448326/85527173 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARHGAP24
Nearest miRNA
hsa-mir-12113/Upstream/2773743; hsa-mir-1243/Downstream/195295;
Nearest TSS
ENST00000502981/Upstream/51687; ENST00000509709/Downstream/43420;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/51357, chr4-CpG: 77/Downstream/1066857
Upstream sequence
ATGTGTATAGGCACTTTAAGCTCCAGAGAAAAGTGTGATGGAAATACCAAGTTACATTATTCTAGGCAAAGTTGAAGAAGGAATAGTTCAAGGGACAATG
Downstream sequence
CTGTCTTTTCTGAGGCTGTATCTCATTAATAATGCATTATAATTTAGAATAAAAAGTAATGTTGCATTTCTTACATTCAGTATAACTCTAGCTTGTTTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate