Basic Information
VIS ID
TVIS44016338
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
89486697/88565546 (Hg38)
End
89486697/88565546 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA4E
Nearest miRNA
hsa-mir-12113/Upstream/1264963; hsa-mir-1243/Downstream/10431841;
Nearest TSS
ENST00000502981/Upstream/41690; ENST00000422770/Downstream/26877;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/41642, chr4-CpG: 150/Downstream/26331
Nearby gene
HERC3(+26877) ;
Upstream sequence
tatatcttcttgctgaattgacccctttatcattatacaatgattttgtctttttatagtttttgtcttgaaatctattttgtctgatataagtatagct
Downstream sequence
actcctactcttttttggtttcgcatggaatatttttttccacccctttattttcagtttatgtgtgtctttataggcaaagtgtgtttcttgtaggcaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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