Basic Information
VIS ID
TVIS44016348
Fusion event
HTLV-1-LOC441098 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
99725477/100389773 (Hg38)
End
99725477/100389773 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
LOC441098
Nearest miRNA
hsa-mir-10397/Upstream/4310561; hsa-mir-103a-1/Downstream/426709;
Nearest TSS
ENST00000502646/Upstream/840341; ENST00000511468/Downstream/11668;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1459946, chr5-CpG: 62/Downstream/145448
Nearby gene
LOC100133050(-1519) ;
Upstream sequence
GGTCACACACGGTGTGAAAAGGCGGCAGATACAGCACCAGGGCAGACACTCGCCCCAAGGGGTGGCTCCCCCAGATCTCAGGCCTCTAGGCCCCATAGAC
Downstream sequence
ACAAGATTCCCCTGCTGCCACGCAGGCGAGGGGAGCCTTTGATGCTGCCACCTCCCTTAGAGCGGGGGTACCGGGTCACTGCTGAAGACCTGCACCTGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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