Basic Information
VIS ID
TVIS44016350
Fusion event
HTLV-1-LOC107986437 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
100248359/100912655 (Hg38)
End
100248359/100912655 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
LOC107986437
Nearest miRNA
hsa-mir-10397/Upstream/96090; hsa-mir-103a-1/Downstream/9601174;
Nearest TSS
ENST00000502646/Upstream/9389; ENST00000506058/Downstream/1231422;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/9221, chr5-CpG: 26/Downstream/1383791
Nearby gene
ST8SIA4(-9370) ;
Upstream sequence
attcattaatcaaaacatatttcctgtgcacatgctctttgccaggcattaaactagacactaaggatatagcagaatacaaaacagaaaaacatcctcc
Downstream sequence
tcttgagggctatcatttttagatgtagaaaggtataataaaaggaaaaaaatggaggtaattattgtgattagtgctatgaaggaaccaacagggcaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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