Basic Information
VIS ID
TVIS44016357
Fusion event
HTLV-1-LOC105379110 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
104637132/105301431 (Hg38)
End
104637132/105301431 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
LOC105379110
Nearest miRNA
hsa-mir-10397/Upstream/4484866; hsa-mir-103a-1/Downstream/5212398;
Nearest TSS
ENST00000502646/Upstream/55067; ENST00000513676/Downstream/91539;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2041582, chr5-CpG: 253/Downstream/2367998
Nearby gene
RAB9BP1(+201333) ;
Upstream sequence
GATATTTACAAAATAACTAGCTACATAAAAGGCAAAGACAAGCTTGTAATTAAAGCTACTTTCAGGTGGTAGCTTCTCTTTAATTATTAATAATTTTGCA
Downstream sequence
TAGTTGGATACATGTTATATGTTGCTGTATACATTTTCAATCTGGATTCTGAAGGCATATTTTGCCTTTAAAAGTCAAAATAATAATCGCTTTTATTTTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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