VISDB Viral Integration Site DataBase

VIS ID

TVIS44016362

Fusion event

HTLV-1-REEP5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q22.2

Reference genome

Start

End

112245826/112910129 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-101-3p ; hsa-mir-30a-5p ; hsa-mir-196b-5p ; hsa-mir-17-5p ; hsa-mir-6721-5p ; hsa-mir-218-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-587 ; hsa-mir-8065 ; hsa-mir-873-5p ; hsa-mir-3616-3p ; hsa-mir-3925-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4797-5p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-3664-5p ; hsa-mir-514a-5p ; hsa-mir-4714-5p ; hsa-mir-552-3p ; hsa-mir-374a-3p ; hsa-mir-34c-3p ; hsa-mir-5586-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-1229-3p ; hsa-mir-1285-5p ; hsa-mir-1304-3p ; hsa-mir-136-5p ; hsa-mir-153-3p ; hsa-mir-1911-3p ; hsa-mir-1972 ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-375 ; hsa-mir-448 ; hsa-mir-5696 ; hsa-mir-579-3p ; hsa-mir-6500-3p ; hsa-mir-664b-3p ; hsa-mir-6739-3p

Nearest miRNA

hsa-mir-10397/Upstream/2396214; hsa-mir-103a-1/Downstream/3345614;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/48579, chr5-CpG: 93/Downstream/11154

Upstream sequence

caatggctcacgcctgtaatcgcagcattttgggaggccaaggagggtggatcacttgaggtcaggagttcaaggccagactggccaacatggtgatacc

Downstream sequence

ccgtctctactaaaaatacaaaaattagccaggcatagtggtgtgcacctgtagtcccagctactcgggaggctgaagcaggagaattacttgaacccgg