Basic Information
VIS ID
TVIS44016382
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
13348616/13348504 (Hg38)
End
13348616/13348504 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/2870359; hsa-mir-103a-1/Downstream/1477425;
Nearest TSS
ENST00000502646/Upstream/172658; ENST00000503244/Downstream/422778;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/552969, chr5-CpG: 26/Downstream/461513
Nearby gene
DNAH5(-341821) ;
Upstream sequence
CCTAAAAGCAAGCTCCACTCATGTAATTTCAAGCTATTTTTACAAACTGTCTCAATAACATTTGCTGTTAAAGCAGCAGTCAGTCCCAAGTCTTCAGTTT
Downstream sequence
CTGTGGTACTAAATTTCTTTCTCCTCATTATATCCCCAGACTCCCATCCATCTGTCCTCAGAGCAGGTGAGATTCTGATGGCTCTGAGAAGTAGTCAATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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