Basic Information
VIS ID
TVIS44016402
Fusion event
HTLV-1-ABLIM3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37/hg19
Start
148621436/149241873 (Hg38)
End
148621436/149241873 (Hg38)
Orient
+
Location type
Intronic
Target gene
ABLIM3
miRNAs that regulate target gene
hsa-mir-214-3p
Nearest miRNA
hsa-mir-10397/Upstream/179464; hsa-mir-103a-1/Downstream/187045;
Nearest TSS
ENST00000502646/Upstream/4425; ENST00000517451/Downstream/1475;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/99969, chr5-CpG: 75/Downstream/29707
Upstream sequence
tgaagagccagcctatgaagaagccaaggaaagacatcccaggcagagggaagagcaCTATCATGTCATGTGACCGCAGGTCATGACAGGAATTGAgagg
Downstream sequence
aagacaggggctacaggactgagtgggtgtagtttggacaaggtctccctctgagtcacagcagagccagggctgaacctcagtctcctgacaccaagct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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