VISDB Viral Integration Site DataBase

VIS ID

TVIS44016417

Fusion event

HTLV-1-WWC1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q34

Reference genome

Start

End

167898619/168471614 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-4258 ; hsa-mir-4707-3p ; hsa-mir-22-3p ; hsa-mir-5698 ; hsa-mir-5001-3p ; hsa-mir-891a-3p ; hsa-mir-143-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-6499-3p ; hsa-mir-2276-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-5693 ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-216a-5p ; hsa-mir-6796-3p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-498 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-212-5p ; hsa-mir-5697 ; hsa-mir-562

Nearest miRNA

hsa-mir-10397/Upstream/305685; hsa-mir-103a-1/Downstream/89282;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/178931, chr5-CpG: 32/Downstream/14678

Upstream sequence

TTGAGGAGGCTGCTCTCTTTGCTGACCCCATGATCTTTTCTGCCCTTCTGTTAAGGGCATTGGCCACAGCAACGGGGCAAATGCCCCAAGCTGGCTGTAA

Downstream sequence

GTGACCCATCCCTTTGGCTCCCATGATTAGACCAAGGAGAGGCATGGGGTCCAGCTGAGCCATTCAGAACCATTCCTTAGCATTTTCCACTCAAAGGTTA