Basic Information
VIS ID
TVIS44016432
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
179642802/180215802 (Hg38)
End
179642802/180215802 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5G
Nearest miRNA
hsa-mir-10397/Upstream/200405; hsa-mir-4638/Downstream/827601;
Nearest TSS
ENST00000502646/Upstream/6649; ENST00000504573/Downstream/27098;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/6358, chr5-CpG: 133/Downstream/75726
Nearby gene
RASGEF1C(-6672) ;
Upstream sequence
aatgccaagaaacagattctccccaagggcctccagaaggaaccagccctgctaacaccttgctttcagcccactaagacccacgctggacttctgaccc
Downstream sequence
acagaactgtgctgctttgagccactacgttggtggtaatttgcgacagcagcaataggaaaggaagacaCCATCCCACAAGAGAGGCTGGGAAAATCGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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