Basic Information
VIS ID
TVIS44016440
Fusion event
HTLV-1-C5orf17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
24065134/24065025 (Hg38)
End
24065134/24065025 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA5E
Target gene
C5orf17
Nearest miRNA
hsa-mir-10397/Upstream/6909033; hsa-mir-103a-1/Downstream/7871077;
Nearest TSS
ENST00000502646/Upstream/113461; ENST00000510391/Downstream/288418;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2605282, chr5-CpG: 68/Downstream/1125369
Upstream sequence
TCAAATATTATCAGTGCATTCttttttgttgttgttgttttttgtttgtgagatggagtctcgctctgtcacccaggctggagtgcagtggcgcagtctc
Downstream sequence
cgctcactgcaagctccacctcccaggttcacgccattctcctgcctcagcctcccaagtagctgggactacaggcgcccaccaccacgcccagctaatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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