Basic Information
VIS ID
TVIS44016460
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
36541604/36541502 (Hg38)
End
36541604/36541502 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/393514; hsa-mir-103a-1/Downstream/2016000;
Nearest TSS
ENST00000502646/Upstream/239388; ENST00000504121/Downstream/64853;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/298940, chr5-CpG: 45/Downstream/148603
Nearby gene
SLC1A3(+64853) ;
Upstream sequence
cagcctgaccaacatggagaaatcccgtctctactaaaaacacaaaattagccgggtgtggtggcaggcgcctgtaattccagctactcgggaggctgag
Downstream sequence
gcagtagaatcgcttgaacctgggaggcagaggttgcagtgaacggagatcacaccactgcactccagcctgggcaataagagcaaaactccatctcaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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