Basic Information
VIS ID
TVIS44016464
Fusion event
HTLV-1-LIFR-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
38644479/38644377 (Hg38)
End
38644479/38644377 (Hg38)
Orient
-
Location type
ncRNA_exonic
Fragile sites / regions
FRA5A
Target gene
LIFR-AS1
Nearest miRNA
hsa-mir-10397/Upstream/86816; hsa-mir-103a-1/Downstream/15307127;
Nearest TSS
ENST00000502646/Upstream/36023; ENST00000511734/Downstream/37693;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/86916, chr5-CpG: 92/Downstream/201023
Upstream sequence
atgggctgaatcccacaggagttagagggaatggacccctgtggcaatccctatgatcagccttcctctcaggttggagaagaatgaagTGCACATCAAC
Downstream sequence
CAAACAGAAGAGAAGCAATTTGGAGGAGGAAAAAATCAGTTCTTCATGAAAGGATCACATTGATCTTGGTAAGTGTAAACTCTAGATGCCCatatggttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate