VISDB Viral Integration Site DataBase

VIS ID

TVIS44016465

Fusion event

HTLV-1-RICTOR integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

p13.1

Reference genome

Start

End

39058515/39058413 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-31-3p ; hsa-mir-18a-5p ; hsa-mir-34a-5p ; hsa-mir-6747-5p ; hsa-mir-3124-3p ; hsa-let-7c-5p ; hsa-mir-16-5p ; hsa-mir-142-3p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-92a-2-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-6825-5p ; hsa-mir-625-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-8069 ; hsa-mir-8062 ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-6841-5p ; hsa-mir-6732-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-6509-5p ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-3160-5p ; hsa-mir-3927-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-128-3p ; hsa-mir-153-5p

Nearest miRNA

hsa-mir-10397/Upstream/500852; hsa-mir-103a-1/Downstream/14893091;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/212039, chr5-CpG: 139/Downstream/15366

Upstream sequence

AAGAAAGGCTAGAAATAGCAAAATAGAAACAGAAAGCAATGAGAGAAACAAAAACAAGGCAGAAAGAGAAACAATCACACAGAGATAGGTTATAAGTATC

Downstream sequence

AATCAGATGTTAGATACTATCAGTCTAATAAAGTTCTAATATATCTATTAGAAAATCCATGACATTACTTTATGACTTCCGTCTATGTAAAACCCGGAGT