Basic Information
VIS ID
TVIS44016496
Fusion event
HTLV-1-LINC01331 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
73758381/74462556 (Hg38)
End
73758381/74462556 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01331
Nearest miRNA
hsa-mir-10397/Upstream/1583893; hsa-mir-103a-1/Downstream/8377599;
Nearest TSS
ENST00000502646/Upstream/127790; ENST00000515528/Downstream/74420;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/552661, chr5-CpG: 160/Downstream/177344
Upstream sequence
GGAAGGTGTAGGAGGACAATGTGTTTTCACTCACTGTCTTTAGGAGACATGGCAAATGAGCAGGCGTTCATTCCCAGCCCAGGAATGAACACCAGTTTGG
Downstream sequence
AAAACCAGTTTTAGTGTCTCACAGACATTTGATTCCTGAGGTTCCAAAGATGTTTTAACTGAATTGTCACATGAATGAAGTTCCCTTCACATCATATTTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate