Basic Information
VIS ID
TVIS44016500
Fusion event
HTLV-1-BHMT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
78408094/79112271 (Hg38)
End
78408094/79112271 (Hg38)
Orient
-
Location type
Intronic
Target gene
BHMT
Nearest miRNA
hsa-mir-10397/Upstream/6233608; hsa-mir-103a-1/Downstream/3727884;
Nearest TSS
ENST00000502646/Upstream/462; ENST00000523508/Downstream/8081;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/42383, chr5-CpG: 193/Downstream/123437
Upstream sequence
CAGCCCAGCTTGGACCAGAGTGCGCCCCAGATCTATGTGATCCTTGCCTCTCAGACCCAAAGGCACCCTCTGAGCCCTCCCTGACGGCTGGGTGTCCCCA
Downstream sequence
GAACTCCGAGCCTTCCAATATCTTCTGAATCTGGCACCCCAAGACCAGAAAACTCCCTAGAGATACTGCTCCTAGCCCCGCAGGCGCGATATCCCGTCCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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