VISDB Viral Integration Site DataBase

VIS ID

TVIS44016504

Fusion event

HTLV-1-MSH3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q14.1

Reference genome

Start

End

80113105/80817286 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-326 ; hsa-mir-92b-3p ; hsa-mir-345-5p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-4635 ; hsa-mir-3686 ; hsa-mir-3182 ; hsa-mir-4742-3p ; hsa-mir-216b-3p ; hsa-mir-1246 ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-1224-3p ; hsa-mir-186-3p ; hsa-mir-3159 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-4743-3p ; hsa-mir-498 ; hsa-mir-6783-3p ; hsa-mir-6888-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-3120-5p ; hsa-mir-6787-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4775 ; hsa-mir-4735-5p ; hsa-mir-6872-3p ; hsa-mir-590-3p ; hsa-mir-3163 ; hsa-mir-145-5p ; hsa-mir-7-5p

Nearest miRNA

hsa-mir-10397/Upstream/7938623; hsa-mir-103a-1/Downstream/2022869;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/162232, chr5-CpG: 136/Downstream/142847

Upstream sequence

acattacagtgtcatgggagcgaggggaaagagtgcttcaagaagaaaagtagtggtcaacagtgctgaaaggtcaggtgagttgaagcctgaaaagtca

Downstream sequence

cctttggtcttagcaaaatagctgtcactaatgaccttagcaggagctgctttcgtggagtggtggggccacactgcagttaaaagagggctaaagagtg