Basic Information
VIS ID
TVIS44016527
Fusion event
HTLV-1-OFCC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
10095942/10095709 (Hg38)
End
10095942/10095709 (Hg38)
Orient
+
Location type
Intronic
Target gene
OFCC1
miRNAs that regulate target gene
hsa-mir-181a-5p
Nearest miRNA
hsa-mir-3691/Upstream/3926274; hsa-mir-10398/Downstream/344008;
Nearest TSS
ENST00000381078/Upstream/933932; ENST00000645232/Downstream/308793;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/696343, chr6-CpG: 35/Downstream/223739
Nearby gene
TFAP2A(-300974) ;
Upstream sequence
GTTTGAGAAAGTGACTTTTCCTGCCTCTGTTTCCCTGCTAGTAATACTGGGTGCTAGCCTCGCTGAATTGTTCATTCACTGCTATCTGTTTTGTTCCCCT
Downstream sequence
TGTCCACTTTGTCAGGAGCACTGGAACGGGATTACCTCCGAGGTCGGCTGGGATCTCACGCATGGAGGATACAAGCATGTAATTCCCTTCTGAAAGCCAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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