Basic Information
VIS ID
TVIS44016531
Fusion event
HTLV-1-LOC105377922 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
106076839/105628964 (Hg38)
End
106076839/105628964 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6F
Target gene
LOC105377922
Nearest miRNA
hsa-mir-10398/Upstream/6504268; hsa-mir-1202/Downstream/1155161;
Nearest TSS
ENST00000381078/Upstream/225880; ENST00000424894/Downstream/3232;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/225582, chr6-CpG: 57/Downstream/352272
Nearby gene
PREP(-225840) ;
Upstream sequence
AACTCCCACTCTCCTTGATAAAGAAAAAACACAAAGAGCACCAACTTCCGAAGGGCTGCTGTGCTGAACTTGAGAGAAATCTTCTCTTTGTTACCAGTTG
Downstream sequence
GGTCAGACTTAGAAACTCTTAAACCGGAGGTCTACTGCACTGTGTGGTGGCAGTCACTTTGCTTAAGTAGAGCTTTGTGGCCACTCATGATAATTCCAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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