Basic Information
VIS ID
TVIS44016534
Fusion event
HTLV-1-GCNT2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
10617319/10617086 (Hg38)
End
10617319/10617086 (Hg38)
Orient
-
Location type
Intronic
Target gene
GCNT2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-3691/Upstream/177292; hsa-mir-10398/Downstream/5524470;
Nearest TSS
ENST00000381078/Upstream/31340; ENST00000379568/Downstream/70464;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/190681, chr6-CpG: 56/Downstream/77298
Upstream sequence
ctggctttacccagtggatcccgcaccagggccgcaggtggagctgcctgccagtcccactccgtgcgcctgcactccttagcctttgggcggtcgatgg
Downstream sequence
gactgggcaccatggagcagggaggggtgctcgttggggaggctctggccgcgcaggagcccatggcggtcggggggaggctcagacatggccggctgca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate