Basic Information
VIS ID
TVIS44016546
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
117345841/117024678 (Hg38)
End
117345841/117024678 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/10240458; hsa-mir-1202/Downstream/2044369;
Nearest TSS
ENST00000381078/Upstream/139889; ENST00000326274/Downstream/240880;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/147136, chr6-CpG: 21/Downstream/238743
Nearby gene
RFX6(+92515) ;
Upstream sequence
atgctatgagagcacataggagagagaccttaaccaggattcagggagtcagaaaaggtctatgcaaaaagcatgaagaataattatacgtttatccagg
Downstream sequence
taaaggcacaagcaagtgtgcaaaaactgtgttcttggaagaggaaacatcatgcacagaggcactggggtcagcatggcagaatggagaaaccaacaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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