Basic Information
VIS ID
TVIS44016560
Fusion event
HTLV-1-PHACTR1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
13230385/13230153 (Hg38)
End
13230385/13230153 (Hg38)
Orient
-
Location type
Exonic
Target gene
PHACTR1
Nearest miRNA
hsa-mir-3691/Upstream/2790359; hsa-mir-10398/Downstream/2911403;
Nearest TSS
ENST00000381078/Upstream/176696; ENST00000481706/Downstream/42059;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/215182, chr6-CpG: 41/Downstream/98202
Upstream sequence
GTCTGCAGGAAGGACTCCTTAGCCATCAAACTCAGCAACAGGCCCTCCAAGCGAGAGCTGGAAGAAAAGAACATCCTTCCCAGGCAGACGGATGAGGAGC
Downstream sequence
GGCTGGAGCTGAGGCAACAGATTGGCACCAAGCTCACCAGGTAGGACAGCGGCACCCTCTGCCTCCCTGGCAGTGGGCCTTTAGCTCTCCAGGTTCTAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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