VISDB Viral Integration Site DataBase

VIS ID

TVIS44016565

Fusion event

HTLV-1-SGK1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q23.2

Reference genome

Start

End

134513458/134192320 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-100-3p ; hsa-mir-6079 ; hsa-mir-374a-3p ; hsa-mir-548aw ; hsa-mir-361-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-4641 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-125a-3p ; hsa-mir-873-5p ; hsa-mir-552-3p ; hsa-mir-4803 ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-5692a ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-3942-3p ; hsa-mir-5682 ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-1252-5p ; hsa-mir-570-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-6871-3p ; hsa-mir-6507-5p ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-548c-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-6809-3p ; hsa-mir-3180-5p ; hsa-mir-4639-5p ; hsa-mir-4753-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-2115-5p ; hsa-mir-4738-5p ; hsa-mir-4302 ; hsa-mir-648 ; hsa-mir-576-3p ; hsa-mir-5571-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-3650 ; hsa-mir-133b

Nearest miRNA

hsa-mir-10398/Upstream/2077057; hsa-mir-1202/Downstream/787018;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/15702, chr6-CpG: 21/Downstream/125339

Nearest cancer related gene

SGK1(OG, No orient, 0)

Upstream sequence

tcccaaagtgctgggattacaggcgtgggtcaccatgcccggccTAAGAGCCAAAATTTTAATCAGTGGGAAATGCTGACTGCCACGCTCATTTAAGAGG

Downstream sequence

AAAGGTCAGGATTTCGTGAGCTGCATTGTTCACTGACATCTACTTTAACGACTCCAGCCCAGCCTGAGCTAATCTTTTCCTAAATCCTTTGCATTTTCTT