Basic Information
VIS ID
TVIS44016573
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
148502303/148181167 (Hg38)
End
148502303/148181167 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/7497284; hsa-mir-1202/Downstream/2921508;
Nearest TSS
ENST00000381078/Upstream/43763; ENST00000367469/Downstream/91137;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/671741, chr6-CpG: 79/Downstream/161122
Nearby gene
SASH1(+161426) ;
Nearest cancer related gene
SASH1(TSG, +161426) ;
Upstream sequence
tagatataccagttggcaaccgagctgagctcccagtcagcagctagtgtcaacacaggccacacgagtgagccatcttgggcatctatcccacttgagc
Downstream sequence
ctttagacccttcaagctccagccgtatgacagatcctggacacagactacccactgagcccagtcaaccctctgggctacaagagacgagcataaactg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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