VISDB Viral Integration Site DataBase

VIS ID

TVIS44016582

Fusion event

HTLV-1-CNKSR3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

q25.2

Reference genome

Start

End

154829310/154508176 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-192-3p ; hsa-mir-3163 ; hsa-mir-338-5p ; hsa-mir-3662 ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-6857-5p ; hsa-mir-450a-2-3p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-6869-5p ; hsa-mir-526b-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-4668-5p ; hsa-mir-7852-3p ; hsa-mir-496 ; hsa-mir-645 ; hsa-mir-6750-3p ; hsa-mir-4662a-5p ; hsa-mir-3152-3p ; hsa-mir-4524a-3p ; hsa-mir-6823-5p ; hsa-mir-575 ; hsa-mir-6858-3p ; hsa-mir-4676-5p ; hsa-mir-4524b-3p ; hsa-mir-135b-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-4252 ; hsa-mir-508-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-1273g-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-377-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-4284 ; hsa-mir-2276-3p ; hsa-mir-4638-5p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-6890-3p ; hsa-mir-1306-5p ; hsa-mir-1228-3p ; hsa-mir-498 ; hsa-mir-4772-3p ; hsa-mir-6736-3p ; hsa-mir-6784-5p ; hsa-mir-876-3p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-374b-3p ; hsa-mir-6715b-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-299-5p ; hsa-mir-329-5p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-1277-5p ; hsa-mir-16-5p ; hsa-mir-497-5p ; hsa-mir-15b-5p ; hsa-mir-6838-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-6878-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-212-5p ; hsa-mir-1224-3p ; hsa-mir-6513-3p ; hsa-mir-8062 ; hsa-mir-6813-3p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-1307-3p ; hsa-mir-5587-5p ; hsa-mir-3620-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-603 ; hsa-mir-4435 ; hsa-mir-3191-5p ; hsa-mir-1288-3p ; hsa-mir-591 ; hsa-mir-3190-5p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-518c-5p ; hsa-mir-3169 ; hsa-mir-6749-3p

Nearest miRNA

hsa-mir-10398/Upstream/3405400; hsa-mir-1202/Downstream/345184;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/468303, chr6-CpG: 141/Downstream/1250

Upstream sequence

GCTCAGAAAAGCCAGGGTGATAAGATGTAACCCTTTCTTTCTGCTACAGcagaactgtccaatagaaatataatggaagccacaaatgtgagccctgtgt

Downstream sequence

tattttagattttctaggagacatatgtaagaaggtaaaaataaacaggtgaagcttattttagtaatatattttatttaacctaacgtatcaaaatact