Basic Information
VIS ID
TVIS44016604
Fusion event
HTLV-1-LOC105374976 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
23601748/23601520 (Hg38)
End
23601748/23601520 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374976
Nearest miRNA
hsa-mir-3691/Upstream/5029640; hsa-mir-10398/Downstream/3546106;
Nearest TSS
ENST00000381078/Upstream/263809; ENST00000475830/Downstream/524602;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1031044, chr6-CpG: 23/Downstream/524561
Nearby gene
NRSN1(+524666) ;
Upstream sequence
taagagtgtctgttgtatgctaatgagatgactggtaggtgggggcccctggatagtttcagaatgggggctggttaccagaaagaccaaagcattatta
Downstream sequence
gaaggtggtaactttcagtcccccaactcaccttcacagtggggagaggggctggatattgacttaatcaccaatggcctgtgatttaatcaatcttgtc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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