Basic Information
VIS ID
TVIS44016607
Fusion event
HTLV-1-ZSCAN26 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
28240199/28272422 (Hg38)
End
28240199/28272422 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZSCAN26
Nearest miRNA
hsa-mir-3143/Upstream/1124734; hsa-mir-10398/Downstream/2311910;
Nearest TSS
ENST00000381078/Upstream/5063; ENST00000259883/Downstream/9150;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/12717, chr6-CpG: 40/Downstream/8967
Upstream sequence
AAACAGGACAACAGGTGGTAAGGGTCAGATGTGCTCTTTTTCAGGAATGCAGGAATTGAGATCTCTGGCCAGACAGGTGGACATGGGCTCATCAGCGGAA
Downstream sequence
GGAGAATTACTAAGCTTTGATTCAGTTTTTTTCCAGTCTAGCTGTTAATTTCCTTAGGTCTTACCTCAACCTTACCTGGCCCTTGCTTGGAGAAAACTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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