Basic Information
VIS ID
TVIS44016622
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
37091237/37123461 (Hg38)
End
37091237/37123461 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-1236/Upstream/500949; hsa-mir-10398/Downstream/431904;
Nearest TSS
ENST00000381078/Upstream/101919; ENST00000468243/Downstream/46742;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/78353, chr6-CpG: 203/Downstream/45833
Nearby gene
PIM1(+46685) ;
Nearest cancer related gene
PIM1(OG, +46685) ;
Upstream sequence
tagtcttcggtgatctggaagggaggaagaaggggaaggaatatccctcaaacccaaccagaagccagaggaggacaggggagcagcacacagaagcctc
Downstream sequence
ctggagcacccagcagggtgcaggcggatggggggcaatctgcaggggcaaacaggagatgttgctagtgctccaaaacaacactccaaagcgtggcact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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