Basic Information
VIS ID
TVIS44016624
Fusion event
HTLV-1-FAM50B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p25.2
Reference genome
GRCh37/hg19
Start
3837055/3836821 (Hg38)
End
3837055/3836821 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAM50B
Nearest miRNA
hsa-mir-4645/Upstream/982714; hsa-mir-10398/Downstream/1311412;
Nearest TSS
ENST00000381078/Upstream/84795; ENST00000380274/Downstream/12565;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/84288, chr6-CpG: 136/Downstream/12216
Nearby gene
FAM50B(+12545) ;
Upstream sequence
GGGGAAGCCCCAAGCACAATGCCATTGGTGTCATGATCACTGACACCATTGACAGCCAGTTATATTGCACATGTGGCCCAGAATGTGCCAAGGAGCCTGA
Downstream sequence
GTCTACTGAAGGACACTATGTATTGAAGCCAAGGACAGAGGGAGGCAGGCTACAGTCCCTGAGATCAACTTCAGCACTCTGAAGGGTAATAATCCTCTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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