Basic Information
VIS ID
TVIS44016629
Fusion event
HTLV-1-ADCY10P1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
41093809/41126070 (Hg38)
End
41093809/41126070 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA6H
Target gene
ADCY10P1
Nearest miRNA
hsa-mir-1236/Upstream/2051689; hsa-mir-10398/Downstream/472653;
Nearest TSS
ENST00000381078/Upstream/28283; ENST00000448827/Downstream/25550;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/24466, chr6-CpG: 64/Downstream/245428
Upstream sequence
tttcatagttatattctctTCCATACTTGAAGATAGCTATCAAGACCCAACCAAGTCCTCTTTCCCTACTTTGATAAAAGAGGAGTTGGTTTGGTATTGG
Downstream sequence
GGGTGGGGTGGATGGTATGTGGAAAATGATAGATAGTTGTTGGCAAAAGGCTAAAATGAGGGATTTGGTGTATGATACAATTCCTCTTCTAGCTATAGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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