Basic Information
VIS ID
TVIS44016640
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
45820969/45853232 (Hg38)
End
45820969/45853232 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-10398/Upstream/655462; hsa-mir-10524/Downstream/6291117;
Nearest TSS
ENST00000381078/Upstream/276462; ENST00000321037/Downstream/84232;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/189155, chr6-CpG: 72/Downstream/161908
Nearby gene
CLIC5(-45221) ;
Upstream sequence
AGCCATAGTAATGGCTCTGCTTGTGTATATATGTGTGTTCGTGTGGGAAAGATGTGTGGAAGTTGTGATATTTTAGCTGAAACCTAGCTATGTGGTAAAG
Downstream sequence
GGTAGGGCATGGGCATGGAAGCAGGATGGTACCAGACATGTTTAAGCTCAGTAGTATCCTAATTTGGCTGGAGCTTCAAATGGAAGAAGAGTGGAAATGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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