VISDB Viral Integration Site DataBase

VIS ID

TVIS44016641

Fusion event

HTLV-1-CLIC5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr6

Cytoband

p21.1

Reference genome

Start

End

45893078/45925341 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-628-5p ; hsa-mir-6807-5p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-4480 ; hsa-mir-4251 ; hsa-mir-539-5p ; hsa-mir-3691-3p ; hsa-mir-5680 ; hsa-mir-1252-3p ; hsa-mir-607 ; hsa-mir-3686 ; hsa-mir-6749-3p ; hsa-mir-642a-5p ; hsa-mir-6826-3p ; hsa-mir-3671 ; hsa-mir-3182 ; hsa-mir-4469 ; hsa-mir-1237-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-483-3p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-6868-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4282 ; hsa-mir-548c-3p ; hsa-mir-4753-3p ; hsa-mir-5579-3p ; hsa-mir-4279 ; hsa-mir-3156-3p ; hsa-mir-6802-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-6845-3p ; hsa-mir-532-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4301 ; hsa-mir-500b-3p

Nearest miRNA

hsa-mir-10398/Upstream/727571; hsa-mir-10524/Downstream/6219008;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/261264, chr6-CpG: 72/Downstream/89799

Upstream sequence

CTATTACAAACAGCCAAACACAACATTTGCCAATATACATAGGTATTGCCAACATGCCAACATGTCATTATTCCGCtttttttttttttttttgagatag

Downstream sequence

agtctcgctctgtcacccaggctggaatgcaatggtgcgatctcagctcactgcaaactccatctccctggctcaagcaattcttctgcctcagcctccc