Basic Information
VIS ID
TVIS44016685
Fusion event
HTLV-1-LOC105377899 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh37/hg19
Start
94270363/93560645 (Hg38)
End
94270363/93560645 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105377899
Nearest miRNA
hsa-mir-10398/Upstream/2038908; hsa-mir-1202/Downstream/4463886;
Nearest TSS
ENST00000381078/Upstream/141098; ENST00000424678/Downstream/326255;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/140686, chr6-CpG: 69/Downstream/2016720
Nearby gene
EPHA7(-141063) ;
Upstream sequence
TTAGAAAACTCTAGTGAGTAATGTGACTCTCCTAAAACATACTGCGTAAAGACTTGATCTTTTATTCTATTACACGAGTTAATGTATTATCCTTGACAAA
Downstream sequence
ACTGGATTCAGTAAGTTATAAGATTTACCTTAGGATCACATTCTGGAGTAAAAAAAAAAATTACTGTAATATTTGACATCACTCTAATCTTTGACCATTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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