Basic Information
VIS ID
TVIS44016712
Fusion event
HTLV-1-LOC105375483 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.32
Reference genome
GRCh37/hg19
Start
123650851/124010797 (Hg38)
End
123650851/124010797 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375483
Nearest miRNA
hsa-mir-10525/Upstream/6990478; hsa-mir-10399/Downstream/3047291;
Nearest TSS
ENST00000635602/Upstream/16166; ENST00000497598/Downstream/21408;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/261228, chr7-CpG: 179/Downstream/21212
Nearby gene
TMEM229A(-20119) ;
Upstream sequence
TTTCAGGGTCTCATTCGTTTCTATTCCACATATTCATTGATATTAAAACCTGCACTTACACTCATTTCCTTCAAATTCATAATTTTGTTTTCATTTCAAA
Downstream sequence
GTTTGGTCTCCTAAGGACTTTACTACGTGAATACAGAATACAGAAGACTCTAACAATGTATGAGGGTTTGAATTTCAGACTTATTCAGTCAGTTTACATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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